Diazepam premedication in children
| Autor: | M. B. Gough, A. A. Northan, C. U. Henderson, D. Fell |
|---|---|
| Rok vydání: | 1985 |
| Předmět: |
Male
Sedation Child Behavior Amnesia Blood Pressure Anxiety Random Allocation Heart Rate Humans Medicine Elective surgery Child Tonsillectomy Diazepam business.industry Respiration Cardiorespiratory fitness Strabismus Anesthesiology and Pain Medicine El Niño Child Preschool Anesthesia Mental Recall Female Premedication medicine.symptom business Preanesthetic Medication medicine.drug |
| Zdroj: | Anaesthesia. 40:12-17 |
| ISSN: | 1365-2044 0003-2409 |
| DOI: | 10.1111/j.1365-2044.1985.tb10494.x |
| Popis: | Summary Oral diazepam 0.25 mg/kg or 0.5 mg/kg was employed as premedication in one hundred and one children undergoing elective surgery. The drug failed to modify the rise in cardiorespiratory indices of pre-anaesthetic anxiety compared with control values, and there was no difference between the two doses assessed by a sedation scoring system. 0.25 mg/kg diazepam produced less sedation in children under 5 years old, compared with those 5 years and older, whereas 0.5 mg/kg produced no difference between the older and younger age groups. The plasma levels of diazepam were greater postoperatively in the 0.5 mg/kg group. There was no relationship between plasma diazepam and recall at induction, and pre-anaesthetic amnesia was not enhanced with the higher premedication dose. |
| Databáze: | OpenAIRE |
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