Influence of electromagnetic waves, with maxima in the green or red range, on the morphofunctional properties of multipotent stem cells

Autor:	A.S. Chernov, A. A. Manokhin, Alexander V. Simakin, Sergey V. Gudkov, Artem M. Ermakov, D. A. Reshetnikov, Yu. A. Kovalitskaya, G. K. Ristsov, R. G. Vasilov
Rok vydání:	2019
Předmět:	Male Light Biophysics Color Bone tissue Electromagnetic radiation Malignant transformation Photostimulation Mice chemistry.chemical_compound medicine Animals Hydrogen peroxide Molecular Biology Cell Proliferation Original Paper Cell growth Mesenchymal Stem Cells Cell Biology Atomic and Molecular Physics and Optics medicine.anatomical_structure Gene Expression Regulation chemistry Multipotent Stem Cell Electromagnetic Phenomena Visible spectrum
Zdroj:	J Biol Phys
ISSN:	1573-0689 0092-0606
Popis:	This paper examines the effect of electromagnetic waves, with maxima in the green or red regions of the spectrum, on the morphofunctional state of multipotent mesenchymal stromal cells. The illumination regimes used in our experiments did not lead to any substantial heating of the samples; the physical parameters of the lighting were carefully monitored. When the samples were illuminated with a green light, no significant photostimulatory effect was observed. Red light, on the other hand, had an evident photostimulatory effect. It is shown that photostimulation with a red light decreases the enzymatic activities of mitochondrial dehydrogenases and enhances the viability of cells, their proliferative activity, and their ability to form bone tissue. It is also established that red light stimulates cell proliferation, while not activating the genes that increase the risk of the subsequent malignant transformation of cells or their death. This paper discusses the possible role of hydrogen peroxide in the processes examined.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db65fc31cdb94ab5b7904ed4a6c3c1c6 https://doi.org/10.1007/s10867-019-09531-7 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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