Intravenous lipid emulsions and human neutrophil function

Autor: Denis English, John N. Lukens, Fayez K. Ghishan, James S. Roloff, Paul Parker, Harry L. Greene
Rok vydání: 1981
Předmět:
Zdroj: The Journal of Pediatrics. 99:913-916
ISSN: 0022-3476
DOI: 10.1016/s0022-3476(81)80019-4
Popis: THE BENEFHS to be gained by adequate nutri t ion in host defense are well recognized? ~ Although the use of fat emulsions has been of value to increase nutrient intake, these emulsions have been noted to markedly impair neutrophil function as judged by in vitro chemotaxis and bactericidal assays? " Consequently, the use of alternate means of supplementing nutri t ion has been suggested. 7 To better define the legitimate place for lipid emulsions in parenteral nutr i t ion therapy, we assessed the effect of two commonly used preparations on several neutrophil functions and addressed the mechanism by which the emulsions interfere with cell function.
Databáze: OpenAIRE