Assessing Real-Time Moderation for Developing Adaptive Mobile Health Interventions for Medical Interns: Micro-Randomized Trial

Autor: Elena Frank, Maureen A. Walton, Yu Fang, Zhenke Wu, Ambuj Tewari, Timothy NeCamp, Srijan Sen, Edward L. Ionides
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Male
020205 medical informatics
mood
Population
Psychological intervention
digital health
physical activity
Health Informatics
02 engineering and technology
lcsh:Computer applications to medicine. Medical informatics
smartphone
law.invention
03 medical and health sciences
0302 clinical medicine
wearable devices
Randomized controlled trial
law
0202 electrical engineering
electronic engineering
information engineering

Medicine
Humans
030212 general & internal medicine
sleep
education
mHealth
mobile health
moderator variables
education.field_of_study
Original Paper
mobile phone
business.industry
lcsh:Public aspects of medicine
ecological momentary assessment
Internship and Residency
lcsh:RA1-1270
Moderation
Digital health
Mental health
Telemedicine
Mood
depression
lcsh:R858-859.7
Female
business
Clinical psychology
Zdroj: Journal of Medical Internet Research
Journal of Medical Internet Research, Vol 22, Iss 3, p e15033 (2020)
ISSN: 1438-8871
1439-4456
Popis: Background Individuals in stressful work environments often experience mental health issues, such as depression. Reducing depression rates is difficult because of persistently stressful work environments and inadequate time or resources to access traditional mental health care services. Mobile health (mHealth) interventions provide an opportunity to deliver real-time interventions in the real world. In addition, the delivery times of interventions can be based on real-time data collected with a mobile device. To date, data and analyses informing the timing of delivery of mHealth interventions are generally lacking. Objective This study aimed to investigate when to provide mHealth interventions to individuals in stressful work environments to improve their behavior and mental health. The mHealth interventions targeted 3 categories of behavior: mood, activity, and sleep. The interventions aimed to improve 3 different outcomes: weekly mood (assessed through a daily survey), weekly step count, and weekly sleep time. We explored when these interventions were most effective, based on previous mood, step, and sleep scores. Methods We conducted a 6-month micro-randomized trial on 1565 medical interns. Medical internship, during the first year of physician residency training, is highly stressful, resulting in depression rates several folds higher than those of the general population. Every week, interns were randomly assigned to receive push notifications related to a particular category (mood, activity, sleep, or no notifications). Every day, we collected interns’ daily mood valence, sleep, and step data. We assessed the causal effect moderation by the previous week’s mood, steps, and sleep. Specifically, we examined changes in the effect of notifications containing mood, activity, and sleep messages based on the previous week’s mood, step, and sleep scores. Moderation was assessed with a weighted and centered least-squares estimator. Results We found that the previous week’s mood negatively moderated the effect of notifications on the current week’s mood with an estimated moderation of −0.052 (P=.001). That is, notifications had a better impact on mood when the studied interns had a low mood in the previous week. Similarly, we found that the previous week’s step count negatively moderated the effect of activity notifications on the current week’s step count, with an estimated moderation of −0.039 (P=.01) and that the previous week’s sleep negatively moderated the effect of sleep notifications on the current week’s sleep with an estimated moderation of −0.075 (P Conclusions These findings suggest that an individual’s current state meaningfully influences their receptivity to mHealth interventions for mental health. Timing interventions to match an individual’s state may be critical to maximizing the efficacy of interventions. Trial Registration ClinicalTrials.gov NCT03972293; http://clinicaltrials.gov/ct2/show/NCT03972293
Databáze: OpenAIRE
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