Superoxide dismutase inhibits cytotoxic killing of Fasciola gigantica newly excysted juveniles expressed by sheep invitro

Autor:	H. Lalrinkima, S.S. Jacob, O.K. Raina, D. Chandra, K. Lalawmpuii, C. Lalchhandama, P. Behera, T.C. Tolenkhomba
Rok vydání:	2022
Předmět:	Fascioliasis Infectious Diseases Sheep Superoxides Superoxide Dismutase Immunology Animals Parasitology General Medicine Fasciola hepatica Fasciola
Zdroj:	Experimental parasitology. 242
ISSN:	1090-2449
Popis:	Fasciola gigantica faces a series of threats from various free radicals produced by the host immune system during its invasion through the abdominal cavity and establishment in the bile duct of ruminants, limiting the fluke viability. The role of the superoxide radical produced by Muzaffarnagari sheep immune effector cells against F. gigantica newly excysted juveniles (NEJs) is highlighted in this study, as is the critical role of superoxide dismutase enzyme (SOD) in dismutation of superoxide radicals derived from host immune effector cells in vitro. Three concentrations of the ovine immune effector cells viz. 2.5, 5, and 10 × 10
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db4f602c75b19b85cc6eb7c99c863a40 https://pubmed.ncbi.nlm.nih.gov/36058254 Zobrazit plný text záznamu Full Text from ScienceDirect