Do Not Hallow until You Are out of the Wood! Ultrasonographic Detection of CPP Crystal Deposits in Menisci: Facts and Pitfalls
| Autor: | Bruno Frediani, V. Picerno, Dario Gambera, Antonella Adinolfi, Mauro Galeazzi, I. Bertoldi, Georgios Filippou, Valentina Di Sabatino, Panagiotis Bozios, Sauro Lorenzini |
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| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: |
musculoskeletal diseases
Male medicine.medical_specialty Article Subject medicine.medical_treatment lcsh:Medicine Knee replacement Osteoarthritis Calcium Pyrophosphate lcsh:Technology Menisci Tibial General Biochemistry Genetics and Molecular Biology chemistry.chemical_compound medicine Humans lcsh:Science General Environmental Science Aged Ultrasonography Aged 80 and over lcsh:T business.industry lcsh:R Calcium pyrophosphate General Medicine Middle Aged medicine.disease musculoskeletal system Surgery body regions chemistry Clinical Study Crystal deposition lcsh:Q Female Radiology business Crystallization psychological phenomena and processes |
| Zdroj: | The Scientific World Journal The Scientific World Journal, Vol 2013 (2013) |
| ISSN: | 1537-744X 2356-6140 |
| Popis: | Purpose. Ultrasonography (US) has been demonstrated to be an important tool in the diagnosis of calcium pyrophosphate (CPP) crystal deposition disease. The aim of our study was to individuate and describe possible pitfalls in US detection of such deposits in menisci.Patients and Methods. We enrolled all patients waiting to undergo knee replacement surgery due to osteoarthritis, for one-month period. Each patient underwent US examination of the knee, focusing on the menisci. After surgery, the menisci were examined by US, macroscopically and microscopically, using the microscopic analysis as the gold standard for CPP deposition.Results. 11 menisci of 6 patients have been studied. Ex vivo examination of menisci performed better in CPP identification than in vivo examination. The possible reasons of misinterpretation or misdiagnosis of the in vivo exam were identified and are extensively described in the paper. Also a new sign of CPP crystal deposits was found.Conclusions. This study permitted to highlight some difficulties in CPP crystal detection by US in menisci. Further studies are needed to define completely US CPP crystal aspect and to improve the sensibility and specificity of US in CPP deposition diagnosis. |
| Databáze: | OpenAIRE |
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