| Autor: |
Katelyn B. Bobek, Nameer S. Ezzat, Brandon S. Jones, Yujia Bian, Thomas E. Shaw, Titel Jurca, Hongya Li, Yu Yuan |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Org Lett |
| ISSN: |
1523-7052 |
| Popis: |
The diverse structures and profound biological activities of lignan natural products have enticed significant effort in the exploration of new methodologies for their total synthesis. We have prepared γ-butyrolactone oximes from readily available δ-nitro alcohols via Boc(2)O mediated cyclization. The mild conditions are compatible with a wide range of functional groups, and this methodology has been applied to the total synthesis of five lignan natural products. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
