Cost-effectiveness of public health interventions against human influenza pandemics in France: a methodological contribution from the FLURESP European Commission project
| Autor: | Adriana Pistol, Ariel Beresniak, John S. Oxford, Christian Napoli, Massimo Fabiani, Marta Barral, Dominique Bremond, Christos Lionis, Stéphane Bonnevay, Laurent Niddam, Charmaine Gauci, Ahmed Bounekkar, Paweł Goryński, Caterina Rizzo |
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| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
Cost effectiveness Cost-Benefit Analysis Population MEDLINE 03 medical and health sciences 0302 clinical medicine Environmental health Influenza Human Pandemic medicine Humans cost-benefit analyses 030212 general & internal medicine education public health interventions against human influenza pandemics Pandemics clinical trials education.field_of_study Cost–benefit analysis Romania 030503 health policy & services Public health electronic health records Public Health Environmental and Occupational Health Vaccination Intervention (law) Italy Influenza Vaccines France Poland Public Health Business 0305 other medical science |
| Zdroj: | Università di Pisa-IRIS |
| ISSN: | 1464-360X 1101-1262 |
| Popis: | Background The FLURESP project is a public health project funded by the European Commission with the objective to design a methodological approach in order to compare the cost-effectiveness of existing public health measures against human influenza pandemics in four target countries: France, Italy, Poland and Romania. This article presents the results relevant to the French health system using a data set specifically collected for this purpose. Methods Eighteen public health interventions against human influenza pandemics were selected. Additionally, two public-health criteria were considered: 'achieving mortality reduction ≥40%' and 'achieving morbidity reduction ≥30%'. Costs and effectiveness data sources include existing reports, publications and expert opinions. Cost distributions were taken into account using a uniform distribution, according to the French health system. Results Using reduction of mortality as an effectiveness criterion, the most cost-effective options was 'implementation of new equipment of Extracorporeal membrane oxygenation (ECMO) equipment'. Targeting vaccination to health professionals appeared more cost-effective than vaccination programs targeting at risk populations. Concerning antiviral distribution programs, curative programs appeared more cost-effective than preventive programs. Using reduction of morbidity as effectiveness criterion, the most cost-effective option was 'implementation of new equipment ECMO'. Vaccination programs targeting the general population appeared more cost-effective than both vaccination programs of health professionals or at-risk populations. Curative antiviral programs appeared more cost-effective than preventive distribution programs, whatever the pandemic scenario. Conclusion Intervention strategies against human influenza pandemics impose a substantial economic burden, suggesting a need to develop public-health cost-effectiveness assessments across countries. |
| Databáze: | OpenAIRE |
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