Epidemiologic and clinical features of Crimean-Congo hemorrhagic fever in southern Africa
| Autor: | M. J. Erasmus, S. P. Shepherd, A. J. Shepherd, G. M. McGillivray, D. E. Gill, L. A. Searle, Robert Swanepoel, P. A. Leman |
|---|---|
| Rok vydání: | 1987 |
| Předmět: |
Crimean–Congo hemorrhagic fever
Zimbabwe Veterinary medicine Cattle Diseases Fluorescent Antibody Technique Tick Birds South Africa Ticks Virology medicine Animals Humans Blood coagulation test Nairovirus biology Outbreak Hemagglutination Inhibition Tests biology.organism_classification medicine.disease Infectious Diseases Tanzania Geography Liver Antibody Formation Hemorrhagic Fever Virus Crimean-Congo Parasitology Arachnid Vectors Cattle Hemorrhagic Fever Crimean Blood Coagulation Tests Hyalomma Crimean Congo hemorrhagic fever virus |
| Zdroj: | The American journal of tropical medicine and hygiene. 36(1) |
| ISSN: | 0002-9637 |
| Popis: | Following the diagnosis in 1981 of the first case of Crimean-Congo hemorrhagic fever (CCHF) in South Africa, an antibody survey was undertaken on cattle sera to determine the distribution of the virus and specific diagnostic tests were routinely applied to specimens from suspected cases of hemorrhagic fever to establish the medical significance of its presence. Antibody to CCHF virus was demonstrated by reversed passive hemagglutination-inhibition technique in 2,460/8,667 (28%) cattle sera and in 140/180 herds tested in South Africa, as well as in 347/763 (45%) cattle sera and in 32/34 (94%) herds tested in Zimbabwe. The antibody was found in all major cattle farming areas, but was of low prevalence along the southern coast where 2 of the 3 species of Hyalomma tick which occur in South Africa are absent. From February 1981 to January 1986, inclusive, 29 indigenous cases of CCHF were diagnosed in 16 outbreaks which arose in various locations throughout South Africa. A further 2 imported cases of CCHF arose in Zaire and Tanzania. The clinical features of infection conformed to the classical descriptions of CCHF in the Soviet Union. The fatal outcome in 11/31 cases indicates that the African disease is no less severe than that which occurs in Eurasia. It is inferred that the virus is widespread in all countries in Africa and Eurasia which lie within the limits of world distribution of ticks of the genus Hyalomma. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|