Characterization and Optimization of Phytosome Formulation Containing Alcohol-free Umckalin from Pelargonium sidoides

Autor:	Ahmet Arif Kurt, İsmail Aslan
Jazyk:	angličtina
Rok vydání:	2020
Předmět:	Liposome biology Traditional medicine Chemistry Liposome Phytosome Umckalin Pelargonium sidoides Characterization Alcohol- free extract General Medicine Alcohol free Pelargonium sidoides Pharmacy biology.organism_classification Eczacılık
Zdroj:	Volume: 3, Issue: 1 49-53 Current Perspectives on Medicinal and Aromatic Plants (CUPMAP)
ISSN:	2619-9645 2667-5722
Popis:	This research study was designed to investigatephysicochemical properties of types of phytosome containing alcohol-freeumckalin from Pelargonium sidoides. Fourteen different phytosomal formulations were prepared by film methodusing P. sidoides in various types of phosphatidylcholine; Phospholipon85 G (P 85 G) and phospholipon 100H (PL 100H). Physicochemical properties were measured by particle size and sizedistribution, zeta potential and polydispersity index of optimum 4-phytosomalformulation. Polarized light microscopy (PLM) techniques were employed forobtaining size distribution and surface appearance and lamellarity. The determination of vesicle types ofphytosomes was performed by using PLM. The most suitable alcohol-freephytosome combination was chosen as PL 100H: DCP: CHOL (10: 1: 4) containing 1% P.S (UP 4) because of its particle size and distribution (
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db289e1059b169e58f3def1627219902 https://dergipark.org.tr/tr/pub/cupmap/issue/55337/737878 Zobrazit plný text záznamu