Amphiphilic Dendrimers Control Protein Binding and Corona Formation on Liposome Nanocarriers

Autor:	Klaus Müllen, Marcel Dillenburger, Jessica Wagner, Tanja Weil, Jennifer Oberländer, David Y. W. Ng, Volker Mailänder, Katharina Landfester, Johanna Simon
Jazyk:	angličtina
Rok vydání:	2020
Předmět:	Dendrimers Polymers Surface Properties Plasma protein binding Catalysis Corona (optical phenomenon) Adsorption Dendrimer Amphiphile Materials Chemistry Humans Liposome Chemistry Metals and Alloys Blood Proteins General Chemistry Surfaces Coatings and Films Electronic Optical and Magnetic Materials Liposomes Ceramics and Composites Biophysics Nanoparticles Protein Corona Nanocarriers Palladium Protein Binding Protein adsorption
Zdroj:	Chemical Communications
Popis:	Amphiphilic polyphenylene dendrimers (PPDs) with distinct lipophilic and positively or negatively charged surface groups were adsorbed onto liposomes and their impact on protein adsorption in blood plasma was studied. The PPD corona reduced binding of specific opsonins and increased the adsorption of proteins controlling cellular uptake based on their surface patches.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db27fd8da2db9a4ba149190e45e19764 https://hdl.handle.net/21.11116/0000-0006-D844-A21.11116/0000-0006-95F4-E Zobrazit plný text záznamu