Low Cholesterol is Associated With Mortality From Stroke, Heart Disease, and Cancer: The Jichi Medical School Cohort Study
| Autor: | Tadao Goto, Kazunori Kayaba, Naoki Nago, Shizukiyo Ishikawa |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2011 |
| Předmět: |
Adult
Male medicine.medical_specialty Heart disease Heart Diseases Epidemiology low cholesterol heart disease Rural Health High cholesterol Japan Risk Factors Internal medicine Cardiovascular Disease Cause of Death Neoplasms cohort study Medicine Humans Prospective Studies Risk factor Sex Distribution Prospective cohort study Mass screening Cause of death Aged business.industry Hazard ratio General Medicine Middle Aged medicine.disease mortality stroke Surgery Cholesterol Original Article Female business liver disease Cohort study Follow-Up Studies |
| Zdroj: | Journal of Epidemiology |
| ISSN: | 1349-9092 0917-5040 |
| Popis: | Background: We investigated the relationship between low cholesterol and mortality and examined whether that relationship differs with respect to cause of death. Methods: A community-based prospective cohort study was conducted in 12 rural areas in Japan. The study subjects were 12334 healthy adults aged 40 to 69 years who underwent a mass screening examination. Serum total cholesterol was measured by an enzymatic method. The outcome was total mortality, by sex and cause of death. Information regarding cause of death was obtained from death certificates, and the average follow-up period was 11.9 years. Results: As compared with a moderate cholesterol level (4.14–5.17mmol/L), the age-adjusted hazard ratio (HR) of low cholesterol ( |
| Databáze: | OpenAIRE |
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