Polio Environmental Surveillance and Its Application to SARS-CoV-2 Detection

Autor:	Hiromu Yoshida
Rok vydání:	2022
Předmět:	Pharmacology Poliovirus Poliovirus Vaccine Inactivated Japan Sewage SARS-CoV-2 Humans RNA Viral Pharmaceutical Science Disease Eradication Wastewater Environmental Monitoring
Zdroj:	YAKUGAKU ZASSHI. 142:11-15
ISSN:	1347-5231 0031-6903
DOI:	10.1248/yakushi.21-00161-1
Popis:	The polio eradication program, launched in 1988, has successfully decreased the number of poliomyelitis patients worldwide. However, in areas with immunization gaps where oral polio vaccine coverage has dropped, outbreaks of more virulent vaccine-derived polioviruses (VDPVs) have become a threat to public health. In Japan, inactivated polio vaccine replaced oral polio vaccine as the routine immunization in 2012. Polio environmental surveillance (ES) has been conducted nationwide since 2013 to efficiently monitor the wild type poliovirus or VDPV, which may be imported from overseas. ES may also be utilized to detect other viruses in stool samples. We propose a method of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) detection based on the polio ES network, and establish a procedure to detect fragments of SARS-CoV-2 genome in wastewater solids. Our findings suggest that polio ES can be used to simultaneously monitor SARS-CoV-2 RNA fragments in sewage waters.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db1bdb64de115f1704e0f36b455f0d63 https://doi.org/10.1248/yakushi.21-00161-1 Zobrazit plný text záznamu