Autor: |
Rachel S. Edgar, Andrew D. Beale, Estere Seinkmane, Edward A. Hayter, Alison J. Inglis, Joseph L. Watson, Emmanuel Derivery, Thomas Pons, Sew Peak Chew, Stefan Matile, Aiwei Zeng, Jason Day, Alessandra Stangherlin, Nicolas Lequeux, Rebecca M. Voorhees, Gerben van Ooijen, Silvia Barbiero, John S. O’Neill, Peter Newham, David C S Wong, Marrit Putker, Eline Bartolami, Alina Guna, David A. Bechtold |
Jazyk: |
angličtina |
Rok vydání: |
2021 |
Předmět: |
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Zdroj: |
Nature Communications, Vol 12, Iss 1, Pp 1-1 (2021) Nature Communications |
Popis: |
Between 6-20% of the cellular proteome is under circadian control and tunes mammalian cell function with daily environmental cycles. For cell viability, and to maintain volume within narrow limits, the daily variation in osmotic potential exerted by changes in the soluble proteome must be counterbalanced. The mechanisms and consequences of this osmotic compensation have not been investigated before. In cultured cells and in tissue we find that compensation involves electroneutral active transport of Na |
Databáze: |
OpenAIRE |
Externí odkaz: |
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