| Autor: |
Janani Indrakumar, Poornima Balan, Padmaja Murali, Anbuthiruselvan Solaimuthu, Ane Nishitha Vijayan, Purna Sai Korrapati |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS). 72 |
| ISSN: |
1878-3252 |
| Popis: |
The highly complex pathophysiology of the wound micro-environment demands the development of a multi-faceted system which would enhance the wound healing cascade. Incorporation of nanotechnology in wound therapeutics has opened up new avenues to tourment the diseased condition. Amongst the various types of nanoparticles molybdenum oxide nanoparticles posses various inherent properties that makes it a versatile material to be used in healing. Incorporation of Molybdenum nanoparticles into collagen scaffolds would provide a synergistic and sequential healing process ensuring the formation of a fully functional tissue.The physico-chemical characterization of the synthesized materials were done using SEM and FT-IR techniques. The bicompatibility and cell proliferation were tested using HaCaT cell lines. Pro-angiogenic ability of the scaffold was tested using CAM assay and Chick aortic arch assay. Finally the in-vivo wound healing ability of the material was tested by creating wound of about 6 cmThe characterization of the scaffold revealed the presence MoOThe fabricated MoO |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect