Cytotoxicity, antibacterial and physicochemical properties of a new epoxy resin-based endodontic sealer containing calcium hydroxide
| Autor: | Fernanda Hecksher, Henrique dos Santos Antunes, Rodrigo Ricci Vivan, Emmanuel João Nogueira Leal Silva, Marco Antonio Hungaro Duarte, Sabrina de Castro Brasil, Victor Talarico Leal Vieira |
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| Rok vydání: | 2020 |
| Předmět: |
Radiodensity
0206 medical engineering 02 engineering and technology Enterococcus faecalis Operative Dentistry and Endodontics 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine MTT assay Cytotoxicity General Dentistry Root Canal Obturation Calcium hydroxide biology Chemistry Research 030206 dentistry Epoxy biology.organism_classification CIENCIAS MÉDICAS [UNESCO] 020601 biomedical engineering visual_art OBTURAÇÃO DO CANAL RADICULAR UNESCO::CIENCIAS MÉDICAS visual_art.visual_art_medium Antibacterial activity Nuclear chemistry |
| Zdroj: | Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual) Universidade de São Paulo (USP) instacron:USP Journal of Clinical and Experimental Dentistry Silva, Emmanuel J. ; Hecksher, Fernanda ; Vieira, Victor T. ; Vivan, Rodrigo R. ; Duarte, Marco Antonio ; Brasil, Sabrina C. ; Antunes, Henrique. Cytotoxicity, antibacterial and physicochemical properties of a new epoxy resin-based endodontic sealer containing calcium hydroxide. En: Journal of Clinical and Experimental Dentistry, 12 6 2020: 533-539 RODERIC: Repositorio Institucional de la Universitat de Valéncia instname RODERIC. Repositorio Institucional de la Universitat de Valéncia |
| Popis: | Background This study evaluated the cytotoxicity, antibacterial and physicochemical properties of a new epoxy resin-based endodontic sealer containing calcium-hydroxide Sealer Plus. AH Plus was used as a reference for comparison. Material and Methods Cytotoxicity evaluation was performed according to ISO-10993-5 specifications using MTT assay to check the 3T3 cells viability at 1- to 4-week periods. Antibacterial activity was evaluated using a direct contact test against Enterococcus faecalis. Radiopacity, solubility and flow evaluations were performed according to ISO-6876/2012 specifications. Setting time was assessed following the ANSI/ADA-standard-n.57. The pH level was measured at 3,24,48,72, and 168 hours. Data were statistically analyzed using t-test. The significance level adopted was P0.05). Direct contact results revealed that both freshly prepared sealers has antibacterial effects against Enterococcus faecalis. However, after 7 days both sealers had lost much of their antibacterial effects. Although AH Plus presented higher radiopacity and flow than Sealer Plus (P0.05). AH Plus showed a higher setting time when compared to Sealer Plus (P |
| Databáze: | OpenAIRE |
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