Change of Cerebral Blood Flow After a Successful Pharmacological Treatment of Phantom Bite Syndrome: A Case Report
| Autor: | Yusuke Sato, Toru Naito, Trang T H Tu, Yojiro Umezaki, Akira Toyofuku, Akira Toriihara |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Mirtazapine
Central nervous system Aripiprazole Case Reports Bite Force 03 medical and health sciences 0302 clinical medicine Sensation Medicine Humans Pharmacology (medical) Abnormal Finding Pharmacology phantom bite syndrome business.industry single-photon emission computed tomography (SPECT) Syndrome Middle Aged Temporomandibular Joint Disorders Antidepressive Agents 030227 psychiatry Bite force quotient medicine.anatomical_structure Treatment Outcome Frontal lobe Cerebral blood flow Anesthesia Cerebrovascular Circulation Drug Therapy Combination Female Neurology (clinical) business occlusal dysesthesia 030217 neurology & neurosurgery medicine.drug |
| Zdroj: | Clinical Neuropharmacology |
| ISSN: | 1537-162X |
| Popis: | Background "Phantom bite syndrome," a persistent complaint of an uncomfortable bite sensation with no obvious occlusal abnormal finding, recently was suggested to be related with central nervous system dysfunction. Here, we report a case of phantom bite syndrome in which the occlusal discomfort was improved with mirtazapine and aripiprazole combination parallel with regional cerebral blood flow change. Case report A 60-year-old-female patient came to our clinic with the chief complaint of a "loosely bite" after dental treatment and various uncomfortable sensations of body sites. One year after the medication therapy, the prosthodontic retreatment was carried out successfully, and a good outcome was obtained for over 24 months so far. In addition, a subsequent change of regional cerebral blood flow was observed in single-photon emission computed tomography: the right and left asymmetry of cerebral blood flow in the frontal lobe has disappeared along with the improvement to the symptoms improvement. Conclusions This case suggests that some central nervous system dysfunction involving dopaminergic system might be related to the pathophysiology of phantom bite syndrome. |
| Databáze: | OpenAIRE |
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