Effect of sedation with butorphanol on variables pertaining to the ophthalmic examination in dogs
| Autor: | Sophie Jugant, Géraldine Jourdan, Alain Regnier, Jean-Yves Douet, Agnès Dongay, Didier Concordet |
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| Rok vydání: | 2018 |
| Předmět: |
Male
Intraocular pressure genetic structures Eye Diseases 040301 veterinary sciences Butorphanol Sedation Diagnostic Techniques Ophthalmological Injections Intramuscular 0403 veterinary science 03 medical and health sciences 0302 clinical medicine Dogs medicine Animals Hypnotics and Sedatives Tear secretion Corneal reflex Dog Diseases Intraocular Pressure General Veterinary Blinking business.industry 04 agricultural and veterinary sciences eye diseases Analgesics Opioid Anesthesia 030221 ophthalmology & optometry Reflex Female sense organs Analysis of variance Nictitating membrane medicine.symptom business medicine.drug |
| Zdroj: | Veterinary ophthalmology. 21(5) |
| ISSN: | 1463-5224 |
| Popis: | OBJECTIVE To evaluate whether sedation with intramuscular butorphanol can interfere with different variables of the ocular examination in dogs. ANIMALS Twenty-two beagles without ophthalmic abnormalities. PROCEDURES Each dog was examined 20 min prior to and again just before administration of butorphanol to establish baseline data. The globe and nictitating membrane position was evaluated, and the following were recorded: menace response, dazzle reflex, corneal blink reflex, phenol red thread tear test (PRT), Schirmer tear test-1 (STT-1), pupil size (PS) measurement, and rebound tonometry. Then, butorphanol was injected intramuscularly at a dose of 0.2 mg/kg and these procedures were repeated 10, 20, 30, and 45 min postadministration. A sedation score graded 0 to 3 was also established at these time points. Statistical analyses were performed on quantitative data using ANOVA. RESULTS The sedative effect was not associated with any changes in globe and nictitating membrane position; did not affect the results of the menace response, dazzle reflex, and corneal blink reflex; and had no significant effect on PRT values. However, butorphanol administration was associated with a statistically significant decrease in STT-1 and PS values (P |
| Databáze: | OpenAIRE |
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