Clinical performance metrics of 3D stereoscopic digital mammography compared with 2D digital mammography: observer study

Autor: Takatoshi Aoki, Yukunori Korogi, Yuko Tashima, Yuzuru Inoue, Keiji Hirata, Yoshika Nagata, Masami Fujii, Akiko Daidoji, Mari Miyata, Takefumi Katsuki, Seiichi Murakami, Fumihiro Tanaka
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Popis: OBJECTIVE: To assess the clinical performance of three-dimensional stereoscopic digital mammography (3DsDM) compared with two-dimensional digital mammography (2DDM) for breast lesion diagnosis with jackknife free-response receiver operating characteristics (JAFROC) observer study. METHODS: 40 pairs of standard-dose 2DDM and their 3DsDM images were used for an observer performance study. A total of 18 lesions were identified as the reference standard of actionable breast lesions (Breast Imaging Reporting and Data System Category 3 or more) by two breast radiologists. Ratings and locations of “lesions” determined by observers were utilized for assessing the statistical significance of differences between eight radiologists’ performances with the 2DDM images and with the 3DsDM images in jackknife free-response receiver operating characteristic analysis. RESULTS: The average figure-of-merit values for all radiologists increased to a statistically significant degree, from 0.859 with the 2DDM images to 0.936 with the 3DsDM images (p < 0.001). The average sensitivity for detecting actionable lesions was improved from 74.3 to 92.4% at a false-positive rate of 0.2 per case by use of the 3DsDM images. The mean reading time per case with 2DDM images was not significantly different from that with 3DsDM images. CONCLUSION: The use of 3DsDM would improve the observer performance for breast lesion without considerably extending the reading time. ADVANCES IN KNOWLEDGE: Use of 3DsDM improves radiologists’ performance for breast lesion detection.
Databáze: OpenAIRE