Medial prefrontal theta phase coupling during spatial memory retrieval
| Autor: | Kaplan, R., Bush, D., Bonnefond, M., Bandettini, P.A., Barnes, G.R., Doeller, C.F., Burgess, N. |
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| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
Neuroinformatics
Male hippocampus Cognitive Neuroscience Prefrontal Cortex Hippocampus Posterior parietal cortex Mnemonic Neuropsychological Tests mPFC Temporal lobe User-Computer Interface 03 medical and health sciences 0302 clinical medicine Parietal Lobe medicine Humans Theta Rhythm Prefrontal cortex Research Articles Spatial Memory 030304 developmental biology Cued speech 0303 health sciences MEG medicine.diagnostic_test Parietal lobe Magnetoencephalography Signal Processing Computer-Assisted oscillations MTL Cues 120 Memory and Space Psychology Neuroscience 030217 neurology & neurosurgery psychological phenomena and processes |
| Zdroj: | Hippocampus Hippocampus, 24, 6, pp. 656-65 Hippocampus, 24, 656-65 |
| ISSN: | 1050-9631 |
| Popis: | Memory retrieval is believed to involve a disparate network of areas, including medial prefrontal and medial temporal cortices, but the mechanisms underlying their coordination remain elusive. One suggestion is that oscillatory coherence mediates inter-regional communication, implicating theta phase and theta-gamma phase-amplitude coupling in mnemonic function across species. To examine this hypothesis, we used non-invasive whole-head magnetoencephalography (MEG) as participants retrieved the location of objects encountered within a virtual environment. We demonstrate that, when participants are cued with the image of an object whose location they must subsequently navigate to, there is a significant increase in 4–8 Hz theta power in medial prefrontal cortex (mPFC), and the phase of this oscillation is coupled both with ongoing theta phase in the medial temporal lobe (MTL) and perceptually induced 65–85 Hz gamma amplitude in medial parietal cortex. These results suggest that theta phase coupling between mPFC and MTL and theta-gamma phase-amplitude coupling between mPFC and neocortical regions may play a role in human spatial memory retrieval. © 2014 The Authors. Hippocampus Published by Wiley Periodicals, Inc. |
| Databáze: | OpenAIRE |
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