Porcine Endogenous Retrovirus Transmission Characteristics of an Inbred Herd of Miniature Swine

Autor:	Beth A. Oldmixon, Carolyn A. Wilson, Clive Patience, Thomas A. Ericsson, M. E. White-Scharf, James C. Wood, Julia L. Greenstein, Henk-Jan Schuurman, Göran Andersson
Rok vydání:	2002
Předmět:	viruses Molecular Sequence Data Immunology Endogenous retrovirus Miniature swine Biology Virus Replication Genes env Microbiology Cell Line law.invention law Virology Animals Humans Cells Cultured Recombination Genetic Base Sequence Porcine endogenous retrovirus Endogenous Retroviruses Sequence Analysis DNA Coculture Techniques In vitro Insect Science Leukocytes Mononuclear Herd Recombinant DNA Swine Miniature Recombination and Evolution Animals Inbred Strains
Zdroj:	Journal of Virology. 76:3045-3048
ISSN:	1098-5514 0022-538X
Popis:	Here we report the identification of inbred miniature swine that failed to produce human-tropic replication-competent porcine endogenous retroviruses (HTRC PERVs), using in vitro coculture assays. When HTRC PERVs were isolated from transmitting animals, all were recombinant viruses, with the receptor-binding domain of PERV-A combining with PERV-C-related sequences.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dadd5502e3c89fa109d65f0c63ce0ce2 https://doi.org/10.1128/jvi.76.6.3045-3048.2002 Zobrazit plný text záznamu