BUN as a risk factor for mortality after coronary artery bypass grafting
| Autor: | W. Dudley Johnson, Kenneth L. Kayser, Evelyn M. Kuhn, Arthur J. Hartz |
|---|---|
| Rok vydání: | 1995 |
| Předmět: |
Pulmonary and Respiratory Medicine
Cardiac function curve Male medicine.medical_specialty urologic and male genital diseases Logistic regression Blood Urea Nitrogen chemistry.chemical_compound Risk Factors Internal medicine Blood plasma Medicine Humans Derivation Risk factor Cardiac Output Coronary Artery Bypass Blood urea nitrogen Aged Retrospective Studies Creatinine urogenital system business.industry Retrospective cohort study Middle Aged female genital diseases and pregnancy complications Surgery Logistic Models chemistry Cardiology Female Cardiology and Cardiovascular Medicine business Biomarkers |
| Zdroj: | The Annals of thoracic surgery. 60(2) |
| ISSN: | 0003-4975 |
| Popis: | Although information on blood urea nitrogen (BUN) is universally available for patients who undergo coronary artery bypass grafting, BUN has not often been considered as a risk factor for mortality. This study assessed BUN as a risk factor for CABG patients.Four data sets were evaluated that differed with respect to the types of patients and available patient information. In each of these data sets logistic regression analysis was used to examine the relationship between BUN and mortality after adjusting for other risk factors.Blood urea nitrogen level was strongly associated with mortality in each of the data sets. After adjustment for the available risk factors other than creatinine level, patients with BUN levels greater than 30 mg/dL had a relative odds of mortality ranging between 1.86 and 2.49 (p0.0001 in three of the data sets). Even after adjustment for creatinine level as well as the other variables, BUN was statistically significant at the p less than 0.01 level for three of the data sets.The results suggest that BUN provides additional information on cardiac function that supplements the information provided by other risk factors. |
| Databáze: | OpenAIRE |
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