Different light-activation systems associated with dental bleaching: a systematic review and a network meta-analysis

Autor: Alessandra Reis, Alessandro D. Loguercio, Patricia Klarmann Ziegelmann, Adrieli Burey, Thalita de Paris Matos, Bianca Medeiros Maran
Rok vydání: 2019
Předmět:
Zdroj: Clinical Oral Investigations. 23:1499-1512
ISSN: 1436-3771
1432-6981
Popis: A systematic review and a network meta-analysis were performed to answer the following research question: “Is there any light-activation protocol capable of improving color change efficacy when associated with an in-office bleaching gel in adults?” A search was performed in PubMed, Scopus, Web of Science, LILACS, BBO, Cochrane Library, and SIGLE without date and/or language restrictions in April 23, 2017 (updated on March 30, 2018). IADR abstracts (1990–2018), unpublished and ongoing trial registries, dissertations, and theses were also searched. Only randomized clinical trials conducted in adults that included at least one group treated with in-office dental bleaching with light activation were included. The risk of bias (RoB) was evaluated using the Cochrane Collaboration tool. A random-effects Bayesian-mixed treatment comparison (MTC) model was used to combine light-activated versus light-free in-office bleaching with direct light-free comparison trials. A meta-analysis with independent analysis (high- and low-concentrate hydrogen peroxide [HP]) was conducted for color change (∆E*, ∆SGU). After the removal of duplicates, title, and abstract screening, 28 studies remained. Nine were considered to be at a low RoB, five were at a high RoB, and the remaining were at an unclear RoB. The MTC analysis showed no significant difference in color change (ΔE* and ΔSGU) between light-activation protocols and light-free in-office bleaching, regardless of the HP concentration in the efficacy of the bleaching. No type of light-activated in-office bleaching was superior to light-free in-office bleaching for both high- and low-concentrate in-office bleaching gels (PROSPERO—CRD42017078743). Although many times dental professionals use “laser whitening” as a form of marketing, this study confirmed that no type of light-activation for in-office bleaching can improve the bleaching efficacy.
Databáze: OpenAIRE