Ethical reappraisal of 15 years of cord-blood transplantation

Autor:	Giuseppe Roberto Burgio, Eliane Gluckman, Franco Locatelli
Rok vydání:	2003
Předmět:	Male medicine.medical_specialty Disease Umbilical cord medicine Humans Intensive care medicine Cord blood transplantation Bone Marrow Transplantation Informed Consent business.industry Patient Selection Infant Newborn General Medicine Bioethics Fetal Blood Surgery Transplantation Fanconi Anemia medicine.anatomical_structure Cord blood Donation Female Stem cell business
Zdroj:	The Lancet. 361:250-252
ISSN:	0140-6736
DOI:	10.1016/s0140-6736(03)12276-3
Popis:	Summary Since the first successful use of cord blood as source of haemopoietic stem cells for transplantation in 1988, more than 2000 patients with malignant or non-malignant disorders have been treated with this procedure. Collection and storage of cord blood has prompted ethical considerations, mainly dealing with the issues of autonomy in making decisions about donation of cord blood, and of privacy and confidentiality in the tests required before use of placental cells for transplantation. The ethical implications of possible storage of cord-blood cells for autologous use has also been discussed. Preimplantation selection of HLA-matched embryos to obtain a donor of cells for cord-blood transplantation of a sibling with a life-threatening disease has raised the issue of the extent to which this approach complies with the principles of bioethics.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dabd16ffc8167529e0563896bc93c30b https://doi.org/10.1016/s0140-6736(03)12276-3 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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