Beneficial effects of Vigna angularis extract in osteoporosis and osteoarthritis

Autor:	Hyung Jin Lim, Seung-Jae Lee, Soyoung Lee, Young-Bin Baek, Kang-Min Lee, Chang-Min Lee, Mun-Chual Rho, Seon Gyeong Bak, Seung Woong Lee, Sang-Ik Park, Sun Hee Cheong
Jazyk:	angličtina
Rok vydání:	2020
Předmět:	0301 basic medicine medicine.medical_specialty Monosodium iodoacetate Osteoporosis Osteoarthritis Vigna 03 medical and health sciences 0302 clinical medicine Biological property Internal medicine medicine Beneficial effects Original Research 030203 arthritis & rheumatology Bone mineral biology business.industry Cartilage monosodium iodoacetate medicine.disease biology.organism_classification osteoporosis osteoarthritis 030104 developmental biology medicine.anatomical_structure Endocrinology ovariectomy Vigna angularis business Food Science
Zdroj:	Food Science & Nutrition
ISSN:	2048-7177
Popis:	In Asia, Vigna angularis (azuki bean) has been used as a traditional medicine to treat various diseases because of its biological properties. Osteoarthritis (OA) and osteoporosis (OP) are common regenerative bone diseases that are characterized by deterioration of joint and bone structure. In this study, we evaluated the effects of Vigna angularis extract (VAE) on monosodium iodoacetate (MIA)‐induced OA and ovariectomy (OVX)‐induced OP models. In the MIA‐induced OA results, severe OA was alleviated by the administration of VAE. Extensive local damage in the cartilage and hemorrhagic and edematous of surrounding tissues were decreased by VAE treatment. Articular cartilage was almost intact except for a focal mild abrasion, and the surface was glistening, similar to that of the normal joint. In the OVX‐induced OP results, bone mineral content (BMC) and bone mineral density (BMD) were recovered by VAE treatment, and it improved the microstructures of bone. These results show that VAE could inhibit OA and OP symptoms. We investigated the regulatory effects of bone diseases of ethanolic extract from Vigna angularis (azuki bean). Vigna angularis (azuki bean) could be serve as natural bone‐regulatory material.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dabb5b2623d932fa2ab938b32cc1bf38 http://europepmc.org/articles/PMC7723184 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
Nepřihlášeným uživatelům se plný text nezobrazuje	K zobrazení výsledku je třeba se přihlásit.