Hyperperfusion on Arterial Spin Labeling MRI Predicts the 90-Day Functional Outcome After Mechanical Thrombectomy in Ischemic Stroke
| Autor: | Sheng Liu, Yi‐cheng Hsu, Zheng‐yu Jia, Xiao-Quan Xu, Hai-Bin Shi, Shan-Shan Lu, Lin-Bo Zhao, Chun-Qiu Su, Fei-Yun Wu, Qiang-Hui Liu, Yue-Zhou Cao |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Population 030218 nuclear medicine & medical imaging Brain Ischemia 03 medical and health sciences 0302 clinical medicine Modified Rankin Scale Internal medicine medicine Humans Radiology Nuclear Medicine and imaging education Stroke Ischemic Stroke Retrospective Studies Thrombectomy Univariate analysis education.field_of_study medicine.diagnostic_test business.industry Magnetic resonance imaging Odds ratio medicine.disease Magnetic Resonance Imaging Confidence interval Treatment Outcome Cerebral blood flow Cardiology business |
| Zdroj: | Journal of magnetic resonance imaging : JMRIReferences. 53(6) |
| ISSN: | 1522-2586 |
| Popis: | BACKGROUND The prognostic significance of hyperperfusion after reperfusion therapy in patients with acute ischemic stroke (AIS) remains controversial. PURPOSE To investigate the clinical factors associated with hyperperfusion, and the 90-day prognostic value of hyperperfusion after mechanical thrombectomy in AIS patients. STUDY TYPE Retrospective. POPULATION/SUBJECTS Fifty-four AIS patients who underwent mechanical thrombectomy. FIELD STRENGTH/SEQUENCE Time-of-flight MR angiography, pulsed arterial spin labeling (ASL), diffusion-weighted imaging (DWI), and susceptibility-weighted imaging were performed at 3.0T within 1 week after thrombectomy. ASSESSMENT Clinical factors including demographics, risk factors, stroke and treatment characteristics were collected and assessed. Hyperperfusion on ASL was defined as a focal increased cerebral blood flow on the affected side ≥130% of its mirror counterpart. Good clinical outcome at 90 days was defined as modified Rankin Scale score of 0-2. STATISTICAL TESTS The interrater agreement was assessed using Cohen's kappa or the intraclass correlation coefficient. The relationship between hyperperfusion and clinical factors were analyzed by appropriate univariate statistics. Predictors of 90-day functional outcome were assessed by univariate analyses followed by multivariate logistic regression analysis and receiver-operating-characteristic curves. RESULTS Thirty-six (66.7%) patients developed hyperperfusion on ASL after thrombectomy. Hyperperfusion was significantly correlated with successful recanalization (P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text