Self-Sampling for Human Papillomavirus in a Community Setting: Feasibility in Hispanic Women
| Autor: | James Hess, Israel De Alba, Alberto Manetta, America Bracho, F. Allan Hubbell, Argyrios Ziogas, Hoda Anton-Culver, Caleb Arias |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
Adult
medicine.medical_specialty Adolescent Epidemiology Papanicolaou stain Sensitivity and Specificity Health care medicine Humans Sampling (medicine) Human papillomavirus Vaginal Smears Gynecology Chi-Square Distribution business.industry Obstetrics Papillomavirus Infections Cancer Hispanic or Latino Gold standard (test) Middle Aged medicine.disease Self Care Oncology Feasibility Studies Community setting Female business Papanicolaou Test Self sampling |
| Zdroj: | Cancer Epidemiology, Biomarkers & Prevention. 17:2163-2168 |
| ISSN: | 1538-7755 1055-9965 |
| DOI: | 10.1158/1055-9965.epi-07-2935 |
| Popis: | Background: The aim of the study was (a) to assess sensitivity and specificity of self-sampling in a community setting for identifying high-risk human papillomavirus (HPV) infection and abnormal Papanicolaou (Pap) smears and (b) to assess satisfaction with this collection method among Hispanic women. Methods: Lay health workers distributed self-collection kits to Hispanic women in the community. Participants collected an unsupervised vaginal sample at home or in the place and time of their preference. Results: A total of 1,213 Hispanics were included and provided a self-sample for HPV testing and were invited for a Pap smear; 662 (55%) of them had a Pap smear and the first 386 of these also had a physician-collected sample for HPV retesting. Using physician collection as the gold standard, unsupervised self-collection had a sensitivity of 90% and specificity of 88% for identifying high-risk HPV. Compared with physician sampling, self-sampling in a community setting had comparable sensitivity for identifying a low-grade lesions or greater in the Pap smear (50% versus 55%; P = 0.45) but lower specificity (94% versus 79%). Overall experience with self-sampling was reported as excellent or very good by 64% and only 2.6% reported a poor or fair experience. Conclusions: Unsupervised self-collection of vaginal samples for HPV testing in a community setting has a high sensitivity for identifying high-risk HPV and a high satisfaction among Hispanics. This approach may benefit populations with limited access to health care or with cultural barriers to cervical cancer screening. (Cancer Epidemiol Biomarkers Prev 2008;17(8):2163–8) |
| Databáze: | OpenAIRE |
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