Early Development of Multiple Epithelial Neoplasms in Netherton Syndrome
| Autor: | A. Manios, J.G. Panayiotides, M. Stephanidou, Konstantin Krasagakis, Despina Ioannidou, Androniki D. Tosca |
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| Rok vydání: | 2003 |
| Předmět: |
Adult
Male Pathology medicine.medical_specialty Skin Neoplasms Congenital ichthyosiform erythroderma Hyperkeratosis Dermatology Neoplasms Multiple Primary Congenital ichthyosis medicine Humans Netherton syndrome integumentary system Ichthyosis business.industry Skin Diseases Genetic Syndrome Ichthyosiform Erythroderma Congenital medicine.disease Dyskeratosis Carcinoma Squamous Cell Skin cancer business Trichorrhexis invaginata |
| Zdroj: | Dermatology. 207:182-184 |
| ISSN: | 1421-9832 1018-8665 |
| DOI: | 10.1159/000071791 |
| Popis: | We report a case of Netherton syndrome manifested as congenital ichthyosiform erythroderma, trichorrhexis invaginata and atopy, who in early adulthood developed multiple, aggressive epithelial neoplasms in sun-exposed areas of the skin, in areas with papillomatous skin hyperplasia and at the left parotid region. The occurrence of cutaneous neoplasia has been reported in syndromes with congenital ichthyosis and suggests that the underlying genetic defects may cause the development of cancer in prone patients. |
| Databáze: | OpenAIRE |
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