PET Findings of Intramedullary Tumors of the Spinal Cord Using [18F] FDG and [11C] Methionine
| Autor: | N. Tomura, Y. Mizuno, Y. Ito, T. Saginoya, K. Watanabe, S.-i. Numazawa, H. Matsuoka |
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| Rok vydání: | 2012 |
| Předmět: |
Adult
Male Ependymoma Hemangioma Cavernous Central Nervous System medicine.medical_specialty Standardized uptake value Astrocytoma Multimodal Imaging Diagnosis Differential Angioma Hemangioma Young Adult Methionine Fluorodeoxyglucose F18 Hemangioblastoma medicine Humans Radiology Nuclear Medicine and imaging Carbon Radioisotopes Spinal Cord Neoplasms Child neoplasms Aged Fluorodeoxyglucose business.industry Middle Aged medicine.disease Spinal cord Spine medicine.anatomical_structure Positron-Emission Tomography Female Neurology (clinical) Radiology Radiopharmaceuticals Tomography X-Ray Computed business Anaplastic astrocytoma medicine.drug |
| Zdroj: | AJNR Am J Neuroradiol |
| ISSN: | 1936-959X 0195-6108 |
| DOI: | 10.3174/ajnr.a3374 |
| Popis: | BACKGROUND AND PURPOSE: Only a few reports on intramedullary tumors of the spinal cord using PET have been published. We report findings of PET by using [18F] fluorodeoxyglucose and [11C] methionine and discuss the usefulness of the findings in patients with intramedullary tumors of the spinal cord. MATERIALS AND METHODS: PET/CT was performed in 9 patients with intramedullary tumors of the spinal cord: Six had ependymomas, 1 had an anaplastic astrocytoma, 1 had a hemangioblastoma, and 1 had a cavernous angioma. The maximum standardized uptake value of the tumor was measured and compared with pathologic findings. RESULTS: The SUVmax of FDG and MET in a case of anaplastic astrocytoma was high. The SUVmax of FDG and MET was relatively high in 4 of 6 cases of ependymoma (excluding myxopapillary ependymomas). A case of hemangioblastoma showed decreased uptake of both FDG and MET (SUVmax = 2.0 and 1.4, respectively). Three cases with hemorrhage (1 case of ependymoma, 1 case of cellular ependymoma, and 1 case of cavernous angioma) showed a relatively increased uptake of FDG. CONCLUSIONS: Both FDG and MET accumulated to a large degree in an anaplastic astrocytoma and accumulated in ependymomas (excluding a myxopapillary ependymoma). FDG can accumulate in tumors with hemorrhage. More investigation of a larger number of patients is required to evaluate the diagnostic value of PET with FDG and MET for imaging intramedullary tumors of the spinal cord. |
| Databáze: | OpenAIRE |
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