Chromatographic evaluation of perfusion on charcoal in uraemia
| Autor: | Roberto Scandurra, Aldo Laganà, Arnaldo Liberti, Laura Politi, Nicola Cerulli |
|---|---|
| Rok vydání: | 1985 |
| Předmět: |
Chromatography
Gas Potassium Sodium Ultrafiltration chemistry.chemical_element fluorescence detetion High-performance liquid chromatography chemistry.chemical_compound Column chromatography medicine Humans Blood urea nitrogen Chromatography High Pressure Liquid Uremia Chromatography Chemistry General Chemistry HPLC UV detection electrochemical detection Perfusion Charcoal Uric acid Spectrophotometry Ultraviolet Dialysis (biochemistry) Activated carbon medicine.drug |
| Zdroj: | Journal of Chromatography B: Biomedical Sciences and Applications. 345:251-258 |
| ISSN: | 0378-4347 |
| DOI: | 10.1016/0378-4347(85)80162-6 |
| Popis: | Chromatography on Bio-Gel P-2 and high-performance liquid chromatography on RP-18 columns monitored with UV, fluorescence and electrochemical detectors have been used to evaluate the efficiency of granular, uncoated, active charcoal to remove from the ultrafiltrates of uraemic patients those organic substances accumulated in the blood that are not easily removed by dialysis. Chromatography on Bio-Gel P-2 and high-performance liquid chromatography on RP-18 columns carried out isocratically and monitored with an electrochemical detector seem very useful for clinical investigation as they increase the information obtained from routine haematochemical analyses such as blood urea nitrogen, creatinine, uric acid and electrolytes (calcium, phosphorus, sodium and potassium). |
| Databáze: | OpenAIRE |
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