Opportunistic bronchopulmonary infections after lung transplantation: clinical and radiographic findings
| Autor: | L. L. Schulman, Revati Shreeniwas, C. C. Mcgregor, John H. M. Austin, Y. M. Berkmen |
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| Rok vydání: | 1996 |
| Předmět: |
Adult
Male medicine.medical_specialty Tuberculosis Time Factors Opportunistic infection Heart-Lung Transplantation medicine.medical_treatment Pneumonia Viral Congenital cytomegalovirus infection Opportunistic Infections Gastroenterology Sensitivity and Specificity Postoperative Complications Internal medicine Bronchoscopy medicine Lung transplantation Aspergillosis Humans Radiology Nuclear Medicine and imaging Lung Lung Diseases Fungal business.industry Pneumonia Pneumocystis Herpes Simplex medicine.disease respiratory tract diseases Surgery Transplantation Radiography Pneumonia medicine.anatomical_structure Cytomegalovirus Infections Female Complication business Lung Transplantation |
| Zdroj: | Radiology. 200(2) |
| ISSN: | 0033-8419 |
| Popis: | To assess clinical and radiographic findings in opportunistic bronchopulmonary infections after lung transplantation.Forty-five episodes of opportunistic bronchopulmonary infection occurred in 27 (35%) of 77 lung transplant recipients during a 4-year period. Causative organisms, radiographic patterns, and mortality were reviewed.Cytomegalovirus (CMV) was the most common pathogen (25 episodes), followed by Aspergillus species (seven episodes), Pneumocystis carinii (six episodes), herpes simplex virus (four episodes), Mycobacterium avium complex (two episodes), and M tuberculosis (one episode). Eighteen of the 25 episodes (72%) of CMV pneumonitis occurred in the first 4 months after transplantation; 24 (96%) occurred within the 1st year. Radiographic patterns of symptomatic CMV pneumonitis were diffuse haziness (60%), focal haziness (33%), and focal consolidation (7%). Aspergillus species locally invaded a necrotic bronchial anastomosis in three patients, each within 4 months of transplantation. P carinii was seen as focal haziness and caused no symptoms. Radiographic findings, when present, were seen almost exclusively in the transplanted lung. Despite three deaths attributable to opportunistic bronchopulmonary infection, the difference between the survival rates of patients with and those of patients without bronchopulmonary infection was not statistically significant (82% and 81%, respectively, 1 year after transplantation).Opportunistic bronchopulmonary infections are common after lung transplantation. The most common pathogen is CMV, which causes diverse chest radiographic patterns. Opportunistic bronchopulmonary infections do not adversely affect overall mortality. |
| Databáze: | OpenAIRE |
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