Aflatoxin M1 Determination in Infant Formulae Distributed in Monterrey, Mexico
| Autor: | Rogelio Salas-García, Patricia A. Quevedo-Garza, Esteban G. Ramos-Peña, G.G. Amador-Espejo, Antonio J. Trujillo |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Aflatoxin
Daily intake Health Toxicology and Mutagenesis lcsh:Medicine Food Contamination Toxicology Body weight 01 natural sciences Risk Assessment Article Dietary Exposure AMF1 0404 agricultural biotechnology Animal science Risk index Neoplasms media_common.cataloged_instance Humans amf1 European union Mexico estimated daily intake media_common Mathematics Monterrey (Mexico) lcsh:R 010401 analytical chemistry Body Weight Infant Newborn Infant 04 agricultural and veterinary sciences 040401 food science Infant Formula 0104 chemical sciences Infant formula infant formulae carcinogenic risk index Child Preschool Aflatoxin M1 Environmental Monitoring |
| Zdroj: | Toxins Volume 12 Issue 2 Toxins, Vol 12, Iss 2, p 100 (2020) |
| ISSN: | 2072-6651 |
| DOI: | 10.3390/toxins12020100 |
| Popis: | The occurrence of aflatoxin M1 (AFM1) in infant formulae commercialized in the metropolitan area of Monterrey (Nuevo Leó n, Mexico) was determined by using immunoaffinity column clean-up followed by HPLC determination with fluorimetric detection. For this, 55 infant formula powders were classified in two groups, starter (49 samples) and follow-on (6 samples) formulae. Eleven of the evaluated samples (20%) presented values above the permissible limit set by the European Union for infant formulae (25 ng/L), ranging from 40 to 450 ng/L. The estimated daily intake (EDI) for AFM1 was determined employing the average body weight (bw) of the groups of age in the ranges of 0&ndash 6 and 6&ndash 12 months, and 1&ndash 2 years. The results evidenced high intake values, ranging from 1.56 to 14 ng/kg bw/day, depending on the group. Finally, with the EDI value, the carcinogenic risk index was determined, presenting a high risk for all the evaluated groups. Based on these results, it is a necessary extra effort by the regulatory agencies to reduce the AFM1 presence in infant formulae consumed in Mexico. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|