Quantitative flow ratio-guided residual functional SYNTAX score for risk assessment in patients with ST-segment elevation myocardial infarction undergoing percutaneous coronary intervention
Autor: | Jiapeng Chu, Jiani Tang, Fei Chen, Chunyu Guan, Yanhua Gao, Jian-Yun Gu, Shengxian Tu, Cheng Yang, Zi Ye, Yan Lai, Xuebo Liu, Yi-An Yao |
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Rok vydání: | 2021 |
Předmět: |
medicine.medical_specialty
medicine.medical_treatment Myocardial Infarction 030204 cardiovascular system & hematology Coronary Angiography Risk Assessment 03 medical and health sciences Percutaneous Coronary Intervention 0302 clinical medicine Risk Factors Clinical Research Internal medicine medicine Humans ST segment cardiovascular diseases 030212 general & internal medicine Myocardial infarction Retrospective Studies business.industry Hazard ratio Percutaneous coronary intervention medicine.disease Confidence interval Treatment Outcome Conventional PCI Cardiology ST Elevation Myocardial Infarction Cardiology and Cardiovascular Medicine business Risk assessment Mace |
Zdroj: | EuroIntervention |
ISSN: | 1969-6213 |
Popis: | BACKGROUND: Functional incomplete revascularisation (IR) is associated with a higher risk of major adverse cardiac events (MACE) during long-term follow-up in patients with ST-segment elevation myocardial infarction (STEMI) undergoing percutaneous coronary intervention (PCI). AIMS: This study aimed to investigate the prognostic ability of quantitative flow ratio (QFR)-guided residual functional SYNTAX score (Q-rFSS) and functional IR in STEMI patients undergoing PCI. METHODS: In total, 354 consecutive STEMI patients who successfully underwent PCI were included. Q-rFSS was defined as residual SYNTAX score (rSS) measured only in vessels with QFR ≤0.8. The primary outcome was MACE (a composite of all-cause mortality, myocardial infarction, and ischaemia-driven revascularisation) at 2 years. RESULTS: At two-year follow-up, functional IR (Q-rFSS ≥1) showed significantly higher risk for MACE than functional complete revascularisation (CR) (Q-rFSS=0) (functional IR vs CR, 22.0% vs 7.4%; hazard ratio [HR] 3.21; 95% confidence interval [Cl]: 1.74 to 5.91; p |
Databáze: | OpenAIRE |
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