Adipose tissue fatty acids in men from two populations with different cardiovascular risk: the LiVicordia study
| Autor: | Bo Zieden, Björn Bergdahl, Algis Abaravicius, Arvydas Kaminskas, Anders G. Olsson, Margareta Kristenson, B Elving, Zita Ausrele Kucinskiene |
|---|---|
| Rok vydání: | 1999 |
| Předmět: |
Male
medicine.medical_specialty Clinical Biochemistry Physiology Adipose tissue Coronary Disease Myristic Acid Body Mass Index Abdominal wall Risk Factors Internal medicine Epidemiology medicine Humans Risk factor Sweden business.industry Vascular disease Fatty Acids alpha-Linolenic Acid Lithuania General Medicine Middle Aged medicine.disease Dietary Fats Coronary heart disease Lipoproteins LDL medicine.anatomical_structure Endocrinology Adipose Tissue Fatty Acids Unsaturated Diet Atherogenic Lipid Peroxidation business |
| Zdroj: | Scandinavian Journal of Clinical and Laboratory Investigation. 59:227-232 |
| ISSN: | 1502-7686 0036-5513 |
| DOI: | 10.1080/00365519950185751 |
| Popis: | The LiVicordia study was set up to investigate possible causes for coronary heart disease mortality in middle-aged Lithuanian men being four times higher than in Swedish men. In a previous part of this study we found lower total and low density lipoprotein (LDL) cholesterol in the Lithuanian men in spite of them having a higher fat intake than in the Swedish men. Their LDL was also more susceptible to oxidation in vitro than was that of the Swedish men. Fat quality can influence LDL oxidation. In order to obtain data on long-term fat quality intake we measured the fatty acid composition of abdominal wall adipose tissue by gas chromatography in men aged 50 years from Vilnius, Lithuania (n=50) and Linköping, Sweden (n=50). Men from Vilnius had a significantly higher percentage of adipose tissue long chain polyunsaturated fatty acids (PUFA) (20:4n6, 20:5n3, 22:5n5, 22:6n3) and lower percentage of saturated fatty acids, especially myristic acid (14:0), 3.4+/-0.7 versus 4.6+/-0.8, p0.0001. The percentage content of adipose tissue linoleic acid (18:2n6) was 11.5+/-2.1 versus 11.0+/-1.4 (n.s.) and of linolenic acid (18:3n3) 0.7+/-0.3 versus 0.6+/-0.2 (n.s.) in men from Vilnius and Linköping, respectively. It is concluded that the adipose tissue content of essential fatty acids is similar in men from Vilnius and men from Linköping and therefore the intake is also likely to be similar. The higher contents of long chain highly unsaturated fatty acids in men from Vilnius may be of importance in the oxidation process of LDL. |
| Databáze: | OpenAIRE |
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