Familial Occurrence of Differentiated (Non-Medullary) Thyroid Cancer
| Autor: | K. Motlik, J. Soumar, D. Pohunková, P. Miřejovský, V. Zamrazil, J. Nĕmec |
|---|---|
| Rok vydání: | 1975 |
| Předmět: |
Male
Oncology endocrine system Cancer Research medicine.medical_specialty Adenocarcinoma Internal medicine Follicular phase medicine Humans Thyroid Neoplasms Neoplasm Metastasis Child Thyroid cancer Lymph node Lung business.industry Thyroid Medullary thyroid cancer Cancer General Medicine Middle Aged medicine.disease medicine.anatomical_structure Female business |
| Zdroj: | Oncology. 32:151-157 |
| ISSN: | 1423-0232 0030-2414 |
| DOI: | 10.1159/000225061 |
| Popis: | Differentiated thyroid cancers were found in mother and son. The diagnosis was made first in the boy where papillary and follicular cancer with lymph node involvement and lung metastatic dissemination was diagnosed at the age of 9. Treatment by surgery, radioiodine and thyroid hormones was highly effective. 1 year later, thyroid surgery was performed on his mother but the diagnosis of poorly differentiated follicular thyroid cancer was made only 4 years later when the primary tumour was already unresectable and distant metastases present. In spite of treatment, the disease followed a lethal course in the mother. The familial occurrence of differentiated thyroid cancer is extremely rare and this report is the first where neither previous radiation exposure nor familial colonic polyposis were detected. |
| Databáze: | OpenAIRE |
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