The Association of Uric Acid Calculi with Obesity, Prediabetes, Type 2 Diabetes Mellitus, and Hypertension
| Autor: | Yi-Ning Lin, Fang-Yeh Chu, Ming-Jang Su, Tzung-Hai Yen, Jung-Li Ho, Pin-Hao Huang, Jen-Tang Sun, Po-Wen Ku, Chih-Chun Chang |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Male
medicine.medical_specialty Article Subject Urinary system 030232 urology & nephrology lcsh:Medicine 030204 cardiovascular system & hematology urologic and male genital diseases Gastroenterology General Biochemistry Genetics and Molecular Biology Prediabetic State 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Internal medicine Statistical significance Diabetes mellitus medicine Humans Prediabetes Obesity Retrospective Studies General Immunology and Microbiology business.industry lcsh:R Type 2 Diabetes Mellitus Retrospective cohort study General Medicine Middle Aged medicine.disease Surgery Uric Acid chemistry Diabetes Mellitus Type 2 Hypertension Uric acid Female Urinary Calculi business Research Article |
| Zdroj: | BioMed Research International BioMed Research International, Vol 2017 (2017) |
| ISSN: | 2314-6133 |
| DOI: | 10.1155/2017/7523960 |
| Popis: | Objectives.To disclose the link between the composition of urolithiasis, especially that of uric acid calculi, and obesity, prediabetes, type 2 diabetes mellitus, and hypertension.Materials and Methods.Patients who had urinary calculi and underwent surgical treatment were registered in the study. The composition of urinary calculi was analyzed and correlated with clinical features and biomedical profiles of the patients before surgical intervention.Results.A total of 666 patients with urolithiasis who underwent surgical management were registered and analyzed. In those who had uric acid calculi, there was a significant association with prediabetic (OR: 20.11, 95% CI: 7.40–54.63,P<0.001) and diabetic states (OR: 11.55, 95% CI: 4.41–29.97,P<0.001). It also seemed that uric acid calculi were related to obesity but there was no statistical significance (OR: 2.45, 95% CI: 0.91–6.62,P=0.078). There was no association of uric acid calculi with hypertension (OR: 1.08, 95% CI: 0.54–2.17,P=0.822) and concurrent urinary tract infection (OR: 0.93, 95% CI: 0.44–1.96,P=0.841).Conclusion.There was a remarkable association of uric acid calculi with prediabetic and diabetic states. The uric acid calculi were also seemingly associated with obesity in patients with urolithiasis undergoing surgical management. |
| Databáze: | OpenAIRE |
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