Fibrolamellar Hepatocellular Carcinoma and Noncirrhotic Hyperammonemic Encephalopathy
| Autor: | Oscar Beltrán, María Carolina Pérez, Carolina Salinas, Enrique Ponce de León, Jorge Ceballos, Martín Garzón, Geovanny Hernández, Rodrigo Daza, Jacqueline Mugnier, Adriana Varón, Oscar Jardey Suarez |
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| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Abdominal pain
medicine.medical_specialty Liver tumor medicine.medical_treatment Clinical Sciences Case Report Medical and Health Sciences Gastroenterology Malaise 03 medical and health sciences Liver disease 0302 clinical medicine Internal medicine Hemofiltration medicine Medical history lcsh:RC799-869 Coma business.industry General Medicine medicine.disease digestive system diseases Fibrolamellar hepatocellular carcinoma 030220 oncology & carcinogenesis 030211 gastroenterology & hepatology lcsh:Diseases of the digestive system. Gastroenterology medicine.symptom business |
| Zdroj: | Case Reports in Hepatology, Vol 2018 (2018) Case Reports in Hepatology Repositorio EdocUR-U. Rosario Universidad del Rosario instacron:Universidad del Rosario |
| ISSN: | 2090-6595 2090-6587 |
| Popis: | Fibrolamellar hepatocarcinoma is an infrequent liver tumor, currently considered to be a variant different from hepatocarcinoma. The differences lie in genomic alterations, a greater prevalence of fibrolamellar hepatocarcinoma in young patients, and its lack of association with underlying liver disease. The clinical presentation is unspecific, with symptoms ranging from abdominal pain, malaise, and weight loss to atypical manifestation which include hyperammonemic encephalopathy. We present the case of a 33-year-old woman with no prior medical history who presented with a coma and a diagnosis of inoperable fibrolamellar hepatocarcinoma requiring a cadaver donor transplant. While she was on the waiting list, she received hemofiltration and ammonium benzoate treatment, with progressive improvement in her state of consciousness. |
| Databáze: | OpenAIRE |
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