Maternal age and the risk of adverse pregnancy outcomes: a retrospective cohort study
| Autor: | Carla Pittini, Ambrogio P. Londero, Lorenza Driul, Angelo Cagnacci, Emma Rossetti |
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| Rok vydání: | 2019 |
| Předmět: |
Adult
medicine.medical_specialty Multivariate analysis Neonatal intensive care unit Adolescent Reproductive medicine Gestational Age lcsh:Gynecology and obstetrics Fetal intraventicular hemorrhage Fetal periventricular leucomalacia Maternal age Pregnancy-related hypertensive disorders Young Adult 03 medical and health sciences 0302 clinical medicine Pre-Eclampsia Pregnancy Risk Factors medicine Humans 030212 general & internal medicine Risk factor Maternal Welfare lcsh:RG1-991 Retrospective Studies Fetus 030219 obstetrics & reproductive medicine Cesarean Section Obstetrics business.industry Pregnancy Outcome Obstetrics and Gynecology Retrospective cohort study Stillbirth medicine.disease Pregnancy Complications Premature Birth Female business Neonatal resuscitation Research Article |
| Zdroj: | BMC Pregnancy and Childbirth BMC Pregnancy and Childbirth, Vol 19, Iss 1, Pp 1-10 (2019) |
| ISSN: | 1471-2393 |
| DOI: | 10.1186/s12884-019-2400-x |
| Popis: | Background The increased potential for negative pregnancy outcomes in both extremes of reproductive age is a well-debated argument. The aim of this study was to analyze the prevalence and the outcome of pregnancies conceived at extreme maternal ages. Methods This retrospective study considered all single consecutive pregnancies delivered in a tertiary referral center between 2001 and 2014. Patients were categorized into 4 groups according to maternal age at delivery ( 40 years). The following outcomes were considered (amongst others): pregnancy-related hypertensive disorders (PRHDs), neonatal resuscitation (NR), neonatal intensive care unit (NICU) admission, periventricular leucomalacia (PVL), and grade 3 and 4 intraventicular hemorrhage (IVH). Results During the considered period 22,933 single pregnancies gave birth in our unit. We observed 71 women aged 40 years. In each year throughout the study period, there was a significant increment in maternal age of 0.041 years (95% CI 0.024–0.058) every new year. Multivariate analysis concluded out that maternal age over 40 years was an independent risk factor for preterm delivery (OR 1.36 95% CI 1.16–1.61, p |
| Databáze: | OpenAIRE |
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