Robust Polytopic-LPV Body-Weight-Dependent Control of Blood Glucose in Type-1 Diabetes

Autor: Saleh Mobayen, Mohammad Hassan Asemani, Navid Vafamand, Gisela Pujol-Vazquez
Přispěvatelé: Universitat Politècnica de Catalunya. Departament de Matemàtiques, Universitat Politècnica de Catalunya. CoDAlab - Control, Modelització, Identificació i Aplicacions
Jazyk: angličtina
Rok vydání: 2021
Předmět:
General Computer Science
Observer (quantum physics)
Informàtica::Automàtica i control [Àrees temàtiques de la UPC]
Quadratic lyapunov function
Linear parameter varying (LPV) model
Quantitative Biology::Tissues and Organs
Controladors programables
Linear matrix
Glucose-insulin system
Body weight
Stability (probability)
linear parameter varying (LPV) model
Bergman model
glucose-insulin system
Robustness (computer science)
Control theory
body-weight effect
medicine
Blood sugar -- Control -- Mathematical models
General Materials Science
Dynamic output controller
Programmable controllers
Mathematics
Type 1 diabetes
dynamic output controller
General Engineering
medicine.disease
TK1-9971
Body-weight effect
Glucèmia -- Control - Models matemàtics
Electrical engineering. Electronics. Nuclear engineering
Zdroj: IEEE Access, Vol 9, Pp 96367-96379 (2021)
UPCommons. Portal del coneixement obert de la UPC
Universitat Politècnica de Catalunya (UPC)
ISSN: 2169-3536
Popis: This paper presents a robust $\boldsymbol {H}_{\infty }$ polytopic Linear Parameter Varying (LPV) controller to regulate the blood glucose level in type-1 diabetes patients. The suggested approach utilizes an observer-based controller and polytopic inexact gain-scheduling scheme to construct the stabilizing injecting insulin resilient against the external meal and snack disturbance in Silico. To assure the closed-loop stability and prescribed $\boldsymbol {H}_{\infty }$ performance, a Quadratic Lyapunov Function (QLF) is used and the stabilization conditions are derived in terms of Linear Matrix Inequalities (LMIs). The conventional minimal Bergman model is improved by considering the effect of body-weight on the glucose-insulin phenomenon and the new body-weight functions are identified based on real data. Then, for the body-weight-dependent Bergman model, a polytopic-LPV model is obtained. Simulations show the advantages of the developed glucose-insulin model and the robustness of the suggested controller in dealing with the effects of a meal for patients with different weights and avoiding hypoglycemia and hyperglycemia disorders.
Databáze: OpenAIRE