Comparison of clinical and environmental isolates of Legionella pneumophila obtained in the UK over 19 years
| Autor: | C.A. Joseph, T. G. Harrison, Norman K. Fry, Nivedita Doshi |
|---|---|
| Jazyk: | angličtina |
| Předmět: |
Microbiology (medical)
Legionella Legionella pneumophila Disease Outbreaks Microbiology Rflp typing monoclonal antibody subgrouping Polymorphism (computer science) Genotype medicine Humans Typing biology typing General Medicine biology.organism_classification medicine.disease United Kingdom Infectious Diseases Epidemiological Monitoring surveillance Legionnaires' disease Legionnaires' Disease Restriction fragment length polymorphism RFLP analysis serogroups Sentinel Surveillance Polymorphism Restriction Fragment Length Environmental Monitoring |
| Zdroj: | Clinical Microbiology and Infection. (1):78-85 |
| ISSN: | 1198-743X |
| DOI: | 10.1111/j.1469-0691.2006.01558.x |
| Popis: | Between January 1980 and December 1998, 3458 cases of Legionnaires’ disease were reported to the national surveillance scheme in England and Wales. Of these, 463 (13.4%) were reported as proven by culture and isolation of Legionella spp., with 96.3% being Legionella pneumophila. Serogroup (Sgp), monoclonal antibody (mAb) subgrouping and restriction fragment length polymorphism (RFLP) analysis data were obtained for 321 (69.3%) of these, of which 284 were classified as being unrelated to any other isolate in the study. Typing data were also available for 117 unrelated environmental isolates of L. pneumophila obtained from England and Wales, giving a total of 401 unrelated isolates in the study. Of the clinical isolates, 88.0% were Sgp1, compared with only 42.7% of environmental isolates (p |
| Databáze: | OpenAIRE |
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