Aggregation-Induced Emission of Tetraphenylethene-Conjugated Phenanthrene Derivatives and Their Bio-Imaging Applications
Autor: | Ilgi Min, Joomin Lee, Kyong-Hoon Choi, Ho-Joong Kim, Sung Cho, Duy Khuong Mai, Bong Joo Park, Temmy Pegarro Vales |
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Jazyk: | angličtina |
Rok vydání: | 2018 |
Předmět: |
General Chemical Engineering
tetraphenylethene 02 engineering and technology Conjugated system silica nanoparticles 010402 general chemistry Photochemistry 01 natural sciences Article lcsh:Chemistry Silica nanoparticles chemistry.chemical_compound Bio imaging emission General Materials Science Aggregation-induced emission Tetrahydrofuran aggregation Phenanthrene 021001 nanoscience & nanotechnology 0104 chemical sciences bio-imaging lcsh:QD1-999 chemistry Intramolecular force 0210 nano-technology |
Zdroj: | Nanomaterials Volume 8 Issue 9 Nanomaterials, Vol 8, Iss 9, p 728 (2018) |
ISSN: | 2079-4991 |
DOI: | 10.3390/nano8090728 |
Popis: | In this study, a series of rationally designed emissive phenanthrene derivatives were synthesized and their aggregation-induced emission (AIE) properties in tetrahydrofuran (THF)/water mixtures were investigated. Two tetraphenylethene (TPE) segments were conjugated to both ends of the phenanthrene core at the para-positions and meta-positions, resulting in pTPEP and mTPEP derivatives, respectively. While the TPE-conjugated phenanthrene derivatives did not show any emission when dissolved in pure THF, they showed strong sky-blue emissions in water-THF mixtures, which is attributed to the restriction of intramolecular motions of TPE segments by aggregation. Furthermore, silica nanoparticles loaded with these AIE-active compounds were prepared and proved to be promising intracellular imaging agents. |
Databáze: | OpenAIRE |
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