Antibacterial thyme oil-loaded organo-hydrogels utilizing cellulose acetoacetate as reactive polymer emulsifier
| Autor: | Xin Shen, Xueling Feng, Liduo Rong, Xiaofeng Sui, Zhiping Mao, Bijia Wang |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Staphylococcus aureus
Polymers Microbial Sensitivity Tests 02 engineering and technology Biochemistry Acetoacetates Thymus Plant 03 medical and health sciences chemistry.chemical_compound Rheology Structural Biology Elastic Modulus Phase (matter) Spectroscopy Fourier Transform Infrared Escherichia coli Plant Oils Fourier transform infrared spectroscopy Cellulose Molecular Biology 030304 developmental biology chemistry.chemical_classification Chitosan 0303 health sciences Hydrogels General Medicine Polymer 021001 nanoscience & nanotechnology Anti-Bacterial Agents chemistry Chemical engineering Emulsifying Agents Self-healing hydrogels Emulsion Emulsions 0210 nano-technology Antibacterial activity |
| Zdroj: | International Journal of Biological Macromolecules. 147:18-23 |
| ISSN: | 0141-8130 |
| Popis: | Organo-hydrogels are widely used in various fields, due to functional organic ingredients immobilized by the gel network or stored and protected by the gels. Herein, cellulose acetoacetate (CAA) served as reactive natural polymer emulsifier to stabilize thyme oil-in-water (O/W) emulsions. Hydroxypropyl chitosan (HPCS) was added to the continuous phase in emulsions to achieve the organo-hydrogel via the enamine bonds under mild conditions. The thyme@CAA emulsion with different loadings of the inner phase (up to 50%) displayed uniform droplets distribution (3–5 μm) and favorable stability. The organo-hydrogel was systematically analyzed by Fourier transform infrared spectroscopy, optical microscope, rheology analyses. The emulsion droplets evenly dispersed in the three-dimensional network. The modulus of organo-hydrogels depended on the viscosity of precursor emulsions and the crosslinking density. The resulting organo-hydrogel displayed favorable antibacterial activity against E. coli and S. aureus. CAA, as the reactive emulsifier and crosslinking agent, was a promising alternative candidate to fabricate a series of organo-hydrogel. |
| Databáze: | OpenAIRE |
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