Effects of Metoprolol and Nebivolol on Exercise Blood Pressure in Patients with Mild Hypertension
| Autor: | Hüseyin Uğur Yazıcı, Hande Ozduman, Yüksel Aydar, Alparslan Birdane |
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| Rok vydání: | 2013 |
| Předmět: |
Male
Article Subject Physical Exertion lcsh:Medicine Blood Pressure lcsh:Technology General Biochemistry Genetics and Molecular Biology Nebivolol law.invention Bruce protocol Randomized controlled trial law medicine Humans Benzopyrans In patient lcsh:Science Antihypertensive Agents General Environmental Science Metoprolol lcsh:T business.industry lcsh:R Exercise stress Mean age General Medicine Middle Aged Treatment Outcome Blood pressure Ethanolamines Anesthesia Hypertension Exercise Test Clinical Study Female lcsh:Q business circulatory and respiratory physiology medicine.drug |
| Zdroj: | The Scientific World Journal, Vol 2013 (2013) The Scientific World Journal |
| ISSN: | 1537-744X |
| DOI: | 10.1155/2013/608683 |
| Popis: | Objectives. We planned to compare the impact of two beta blockers, metoprolol and nebivolol, on arterial blood pressure during exercise in patients with mild hypertension.Methods. A total of 60 patients (13 males, 47 females; mean age: years) were enrolled in the present study. The patients were randomly selected to receive either nebivolol 5 mg/day () or metoprolol 50 mg/day () for 8 weeks. At the end of the 8th week, each of the patients received exercise stress test according to Bruce protocol and their blood pressures were remeasured after rest, exercise, and recovery.Results. Blood pressures were determined to be similar between metoprolol and nebivolol groups during rest, exercise, and recovery periods. Metoprolol and nebivolol achieved similar reductions in blood pressures during rest and exercise. However, five patients in nebivolol group and four patients in metoprolol group developed exaggerated BP response to exercise but the difference between metoprolol and nebivolol was not meaningful ().Conclusion. The results of the present study showed that metoprolol and nebivolol established comparable effects on the control of blood pressures during exercise in the patients with mild hypertensions. |
| Databáze: | OpenAIRE |
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