Transplant Tourism Outcome: A Single Center Experience
| Autor: | Lutfi A. Alkurbi, Chaker N. Adra, Mohamed Said Abdelsalam, Mamdouh Albaqumi, Abdelmoneim Eldali, Mohamed M. Shukri, Saad Alghamdi, Sumaya A. Askandrani, Zahid Nabi, Dania Alkhafaji |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
Adult
Graft Rejection Male Reoperation medicine.medical_specialty Pediatrics Philippines Single Center chemistry.chemical_compound Medical Tourism medicine Humans Pakistan Seroconversion Survival analysis Immunosuppression Therapy Transplantation Creatinine business.industry Incidence (epidemiology) Graft Survival Hepatitis C Middle Aged medicine.disease Kidney Transplantation Survival Analysis Tissue Donors Surgery Renal Replacement Therapy Transplant tourism surgical procedures operative chemistry Cytomegalovirus Infections Egypt Female business Follow-Up Studies |
| Zdroj: | Transplantation. 90:184-188 |
| ISSN: | 0041-1337 |
| DOI: | 10.1097/tp.0b013e3181e11763 |
| Popis: | Background Transplant tourism is the term used for patients who travel abroad for transplantation. Transplant tourism has always been surrounded with controversy regarding how these organs were obtained, the donor's care after transplantation, and the recipient outcome. Many authors have found that the outcome of the recipients in transplant tourism is inferior to those transplanted in their own countries. However, most these studies were small, with the latest one including only 33 patients. Here, we describe the outcome of 93 patients who were transplanted abroad compared with local transplantation. Material and methods All transplant patients who were followed up at our Nephrology Clinic from 1998 until 2008 were identified using our data base system. We selected patients transplanted from 2003 and forward because the computerized system for laboratory and electronic records began operation that year. Results A total of 165 patients were identified (93 in the tourist group and 72 in the local one). Transplant tourists had a higher rate of acute rejection in the first year compared with local transplantation (27.9% vs. 9.9, P=0.005), higher mean creatinine at 6 months and 1 year (120 vs. 101 micromol/L, P=0.0007, 113 vs. 98 micromol/L, P=0.008). There was no statistical difference in graft or patient survival in 1 or 2 years after transplantation. However, transplant tourist had a higher rate of cytomegalovirus infection (15.1% vs. 5.6%, P=0.05) and hepatitis C seroconversion (7.5% vs. 0%, P=0.02). Conclusion Transplant tourists had a more complex posttransplantation course with higher incidence of acute rejection and infectious complications. |
| Databáze: | OpenAIRE |
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