A formal total asymmetric synthesis of (+)-thienamycin

Autor: Stephen G. Davies, Jeffrey Mckenna, Charles J. R. Hedgecock
Rok vydání: 1995
Předmět:
Zdroj: Tetrahedron: Asymmetry. 6:2507-2510
ISSN: 0957-4166
DOI: 10.1016/0957-4166(95)00327-l
Popis: Synthesis of an enantiomerically pure intermediate to (+)-thienamycin is presented: the pivotal reaction in this sequence is the highly diastereoselective Michael addition of a differentially protected lithium amide.
Databáze: OpenAIRE