A formal total asymmetric synthesis of (+)-thienamycin
Autor: | Stephen G. Davies, Jeffrey Mckenna, Charles J. R. Hedgecock |
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Rok vydání: | 1995 |
Předmět: | |
Zdroj: | Tetrahedron: Asymmetry. 6:2507-2510 |
ISSN: | 0957-4166 |
DOI: | 10.1016/0957-4166(95)00327-l |
Popis: | Synthesis of an enantiomerically pure intermediate to (+)-thienamycin is presented: the pivotal reaction in this sequence is the highly diastereoselective Michael addition of a differentially protected lithium amide. |
Databáze: | OpenAIRE |
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