Use of oxidized regenerated cellulose to achieve hemostasis during laparoscopic cholecystectomy: a retrospective cohort analysis

Autor: Mauro Longoni, Emilia Masci, Giuseppe Faillace
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Male
Topical hemostat
Cirrhosis
Blood Loss
Surgical
lcsh:Medicine
0302 clinical medicine
Cholelithiasis
Outcome Assessment
Health Care
Medicine
lcsh:QH301-705.5
Aged
80 and over
General Medicine
Middle Aged
Oxidized regenerated cellulose
Research Note
medicine.anatomical_structure
Cholecystectomy
Laparoscopic
030220 oncology & carcinogenesis
030211 gastroenterology & hepatology
Female
Adult
medicine.medical_specialty
Adolescent
Hemorrhage
General Biochemistry
Genetics and Molecular Biology
03 medical and health sciences
Young Adult
Laparoscopic cholecystectomy
Carcinoma
Humans
Cellulose
Oxidized
lcsh:Science (General)
Aged
Retrospective Studies
Hemostat
Hemostasis
business.industry
Hemostatic Techniques
Gallbladder
Bleeding
lcsh:R
Retrospective cohort study
medicine.disease
Surgery
lcsh:Biology (General)
business
lcsh:Q1-390
Zdroj: BMC Research Notes, Vol 11, Iss 1, Pp 1-5 (2018)
BMC Research Notes
ISSN: 1756-0500
DOI: 10.1186/s13104-018-3344-3
Popis: Objective Laparoscopic cholecystectomy is the first-choice treatment for symptomatic cholelithiasis. Though generally safe, this procedure is not without complications, with bleeding the most frequent cause of conversion to open cholecystectomy. Oxidized regenerated cellulose (ORC) added to conventional hemostatic strategies, is widely used to control bleeding during surgery despite limited evidence supporting its use. This retrospective study analyzed patients undergoing laparoscopic cholecystectomy in an Italian center over a 16-month period, between October 2014 and February 2016, who experienced uncontrollable bleeding despite the use of conventional hemostatic strategies, requiring the addition of ORC gauze (Emosist®). Results Of the 530 patients who underwent laparoscopic cholecystectomy, 24 (4.5%) had uncontrollable bleeding from the liver bed. Of these, 62.5% had acute cholecystitis and 33.3% chronic cholecystitis; 1 patient was diagnosed with gallbladder carcinoma, postoperatively. Most patients had comorbidities, 16.7% had liver cirrhosis, and 37.5% used oral anticoagulants. The application of ORC rapidly controlled bleeding in all patients. Patients were discharged after a mean duration of 2.2 days. ORC was easy to use and well tolerated. Bleeding complications remain a relevant issue in laparoscopic cholecystectomy. ORC was able to promptly stop bleeding not adequately controlled by conventional methods and appears, therefore, to be a useful hemostat.
Databáze: OpenAIRE
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