Lung Transplantation for Treatment of Pulmonary Hypertension in Dogs
| Autor: | James D. Hardy, Suhayl S. Saleh |
|---|---|
| Rok vydání: | 1968 |
| Předmět: |
Pulmonary Circulation
medicine.medical_specialty Hypertension Pulmonary medicine.medical_treatment Pulmonary insufficiency Dogs Oxygen Consumption Internal medicine medicine.artery Thiamylal medicine Animals Transplantation Homologous Lung transplantation Lung business.industry Blood Pressure Determination medicine.disease Pulmonary hypertension Pulmonary embolism Surgery medicine.anatomical_structure Pulmonary artery Vascular resistance Cardiology Vascular Resistance Barium Sulfate Pulmonary Embolism business Lung Transplantation medicine.drug |
| Zdroj: | Archives of Surgery. 96:340 |
| ISSN: | 0004-0010 |
| DOI: | 10.1001/archsurg.1968.01330210018004 |
| Popis: | THE clinical applications of lung transplantation for the treatment of pulmonary insufficiency have been few.1-3Although all recipients died within a period of one to three weeks, the transplanted lungs functioned reasonably well. Thus, it is of potential clinical importance to investigate the value of lung transplantation for the treatment of pulmonary hypertension. It is logical to assume that the substitution of a lung with normal pulmonary vascular resistance for one that is diseased should result in lowering of the pulmonary artery pressure and improvement of blood flow. The present study was undertaken to probe the validity of such a hypothesis. Materials and Methods Throughout the experiments adult mongrel dogs weighing 12 to 15 kg (26.4 to 33 lb) were used. Group 1 —Homotransplantation. —Twenty-two dogs were lightly anesthetized with thiamylal anesthesia administered intravenously and a No.6 cardiac catheter was advanced into the right ventricular cavity through the external |
| Databáze: | OpenAIRE |
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