Comparing ginger and vitamin B6 for the treatment of nausea and vomiting in pregnancy: a randomised controlled trial
| Autor: | Jenabi Ensiyeh, Mohammad-Alizadeh C. Sakineh |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Adult
Vomiting Nausea Visual analogue scale Ginger law.invention Young Adult Double-Blind Method Randomized controlled trial Pregnancy law Maternity and Midwifery medicine Humans Young adult Dose-Response Relationship Drug business.industry Obstetrics and Gynecology medicine.disease Vitamin B 6 Pregnancy Complications Treatment Outcome Anesthesia Antiemetics Women's Health Gestation Female medicine.symptom Vitamin b6 business Phytotherapy |
| Zdroj: | Midwifery. 25:649-653 |
| ISSN: | 0266-6138 |
| Popis: | Objective to compare the effectiveness of ginger and vitamin B6 for the treatment of nausea and vomiting in early pregnancy. Methods double-blind randomised controlled trial. Pregnant women with nausea, who first attended the antenatal clinic at or before 17 weeks gestation, were invited to participate in the study. Over a 3-month period, 70 women were randomised to receive either ginger 1g/day or vitamin B6 40mg/day for 4 days. Subjects graded the severity of their nausea using a visual analogue scale, and recorded the number of vomiting episodes in the 24 hours before treatment and during 4 consecutive days while taking treatment. At 7-day follow-up, women reported any changes in the severity of their symptoms. Results compared with baseline, the decrease in the visual analogue scores of post-therapy nausea in the ginger group was significantly greater than that for the vitamin B6 group ( p =0.024). The number of vomiting episodes decreased in both groups, and there was no significant difference between the groups. In the ginger group, 29/35 women reported an improvement in nausea symptoms, compared with 23/34 women in the vitamin B6 group ( p =0.52). Conclusion ginger is more effective than vitamin B6 for relieving the severity of nausea, and is equally effective for decreasing the number of vomiting episodes in early pregnancy. |
| Databáze: | OpenAIRE |
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