Safety and feasibility in highly concentrated contrast material power injections for CT-perfusion studies of the brain using central venous catheters

Autor: Sven O. Eicker, Stephan Macht, Sebastian Braun, Bernd Turowski, Konrad Rybacki, Christian Mathys, Gerald Antoch, Kerim Beseoglu
Rok vydání: 2012
Předmět:
Zdroj: European Journal of Radiology. 81:1883-1885
ISSN: 0720-048X
Popis: Introduction CT perfusion studies play an important role in the early detection as well as in therapy monitoring of vasospasm after subarachnoid hemorrhage. High-flow injections via central venous catheters are not recommended but may sometimes be the only possibility to obtain high-quality images. Materials and methods We retrospectively analyzed our data for CT perfusions performed with power injection of contrast material with an iodine concentration of 400 mg/ml via the distal 16G lumen of the Arrow three and five lumen central venous catheter with preset flow rates of 5 ml/s. Results 104 examinations with central venous catheters were evaluated (67 with five lumen and 37 with three lumen). No complications were observed. Mean flow rates were 4.4 ± 0.5 ml/s using the three lumen catheter and 4.6 ± 0.6 ml/s using the five lumen catheter respectively. The mean injection pressure measured by the power injector was 200.7 ± 17.5 psi for the three lumen central venous catheter and 194.5 ± 6.5 psi for the five lumen catheter, respectively. Conclusion Following a strict safety protocol there were no complications associated with power injections of contrast material containing 400 mg iodine/ml with preset flow rates up to 5 ml/s via the distal 16G lumen of the Arrow multi-lumen central venous catheter. However, since power-injections are off-label use with Arrow central venous catheters, this procedure cannot be recommended until potential safety hazards have been ruled out by the manufacturer.
Databáze: OpenAIRE