Validation of the 'Test of the Adherence to Inhalers' (TAI) for Asthma and COPD Patients

Autor: Manuel Angel Villanueva, Vicente Plaza, Luís Manuel Entrenas Costa, Francisco-Javier Gonzalez-Barcala, Juan Luis Rodriguez Hermosa, Anna Sala Cunill, JUAN FRANCISCO MEDINA GALLARDO, Enrique Burches, MARISOL DOMINGUEZ ALVAREZ, DOLORES CORBACHO, Concepción Fernández-Rodríguez, Pablo Rubinstein-Agunin, Bernardino Alcázar-Navarrete, Francisco Ortega-Ruiz, Kike Cimas, Leovigildo Ginel-Mendoza, Myriam Calle Rubio, Dolores Hernandez, Luis Puente-Maestu, Aurelio Arnedillo Munoz, José Serrano-Pariente, ALBERTO FERNANDEZ-VILLAR, Cristina Martinez-Gonzalez, Ana Fernández-Tena, Ana Fatima Viejo-Casas, Jose gregorio Soto campos, Francisco Casas, Rubén Andújar-Espinosa, Borja G Cosio
Rok vydání: 2016
Předmět:
Male
Questionnaires
Health Knowledge
Attitudes
Practice
área bajo la curva
Psychometrics
Cross-sectional study
Copd patients
humanos
anti-asthmatic agents
Pharmaceutical Science
Pilot Projects
broncodilatadores
Pulmonary Disease
Chronic Obstructive
0302 clinical medicine
Inhalers
Surveys and Questionnaires
Pharmacology (medical)
pulmonary disease
chronic obstructive
drug therapy
030212 general & internal medicine
Lung
mediana edad
pulmonary disease
Original Research
administration and dosage
anciano
COPD
chronic obstructive
proyectos piloto
adulto
Middle Aged
humanities
drug therapy
Bronchodilator Agents
Test (assessment)
asma
Homogeneous
Area Under Curve
Female
Adult
Pulmonary and Respiratory Medicine
medicine.medical_specialty
Anti-asthmatic agents
administration and dosage
Medication Adherence
nebulizadores y vaporizadores
03 medical and health sciences
Cronbach's alpha
curva ROC
adhesión a la medicación
Administration
Inhalation
Criterion validity
medicine
Humans
anti-asthmatic agents
administration and dosage
inhalers
Internal validity
Medication non-adherence
Medication adherence
validation studies
Aged
Asthma
business.industry
Nebulizers and Vaporizers
Reproducibility of Results
Construct validity
Pulmonary disease
chronic obstructive
drug therapy
questionnaires
medicine.disease
reproducibilidad de resultados
psicometría
Cross-Sectional Studies
pulmón
ROC Curve
030228 respiratory system
Validation studies
Spain
medication non-adherence
Physical therapy
business
estudios transversales
Zdroj: Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Journal of Aerosol Medicine and Pulmonary Drug Delivery
RUO. Repositorio Institucional de la Universidad de Oviedo
instname
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
ISSN: 1941-2711
Popis: Background: To validate the Test of Adherence to Inhalers' (TAI), a 12-item questionnaire designed to assess the adherence to inhalers in patients with COPD or asthma. Methods: A total of 1009 patients with asthma or COPD participated in a cross-sectional multicenter study. Patients with electronic adherence 80% were defined as adherents. Construct validity, internal validity, and criterion validity were evaluated. Self-reported adherence was compared with the Morisky-Green questionnaire. Results: Factor analysis study demonstrated two factors, factor 1 was coincident with TAI patient domain (items 1 to 10) and factor 2 with TAI health-care professional domain (items 11 and 12). The Cronbach's alpha was 0.860 and the test-retest reliability 0.883. TAI scores correlated with electronic adherence (=0.293, p=0.01). According to the best cut-off for 10 items (score 50, area under the ROC curve 0.7), 569 (62.5%) patients were classified as non-adherents. The non-adherence behavior pattern was: erratic 527 (57.9%), deliberate 375 (41.2%), and unwitting 242 (26.6%) patients. As compared to Morisky-Green test, TAI showed better psychometric properties. Conclusions: The TAI is a reliable and homogeneous questionnaire to identify easily non-adherence and to classify from a clinical perspective the barriers related to the use of inhalers in asthma and COPD.
This study was funded by the Integrated Research Asthma Program (PII Asthma) together with the Integrated Research COPD Program (PII COPD) of the Spanish Respiratory Society (SEPAR). Unconditional funding was provided by Chiesi, who did not participate in data collection, interpretation of the results, or writing of the manuscript.
Databáze: OpenAIRE
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